Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome

Very long and technical article. 22 patients and 30 healthy controls were tested for certain cells that are part of the immune system. They found an unaffected B-cell compartment, a biased NK-cell phenotype and a poorly responsive T-cell compartment as the main immune features of ME/CFS affected individuals. The striking down modulation of T cell mediated immunity may help to understand intercurrent viral infections in CFS.